Image Gallery
Recent Video
Lipid Droplet / Microvasculature visualized in vivo in 3D in the liver of Non-Alcoholic Fatty Liver Disease (NAFLD) mouse model
Liver Fibrosis visualzied in vivo by Second Harmonic Generation (SHG) Imaging in live nonalcholic fatty liver mouse model
Operation of custom-design, video-rate, intravital confocal microscopy system; starred by K. Choe
We are focusing on the development of the novel in vivo visualization techniques for the live animal in a single cell to single molecule resolution. In a recent decade, rapid advances of in vivo micro-visualization technologies have allowed us to catch a glimpse of numerous exciting processes such as gene expression, regulation, protein activity, drug delivery, systemic cell trafficking, cell-cell interaction, physiological response to external stimuli in the natural microenvironment in vivo. We're now on the verge of a new era of micro-nano-scale in vivo visualization technologies those can be utilized as a novel tool for basic and translational biomedical research as well as  a valuable clinical tool for cellular-level diagnosis and monitoring.

Our ultimate goal is to open up a new avenue to answer questions in biomedical science those are important but difficult to investigate by pioneering innovative visualization technology. We are looking for a talented student and researcher in multiple disciplines including engineering, physics, chemistry, biology and medicine as an active interdisciplinary team-work is the cornerstone to accomplish our goal.
[Notice] Positions open for graduate student (MS/PhD), Post-doctoral researcher  [email]

[Paper]  In Intravital longitudinal imaging of hepatic lipid droplet accumulation in a murine
               model for nonalcoholic fatty liver disease
               Biomedical Optics Express, 11(9):5132-5146 (2020),  Editor's Pick

[Paper]  In vivo longitudinal visualization of the brain neuroinflammatory response at the
               cellular level in LysM-GFP mice induced by 3-nitropropionic acid
               Biomedical Optics Express, 11(8):4835-4847 (2020)
   
[Paper]  In vivo imaging of the hyaloid vascular regression and retinal and choroidal vascular
               development in rat eyes using optical coherence tomography angiography
               Scientific Reports, 11:12901 (2020)

[Paper]  Micromirror-embedded coverslip assembly for bidirectional microscopic imaging
               Micromachines, 11(6):582 (2020)
   
[Paper]  Intraocular distribution and kinetics of intravitreally injected antibodies and
               nanoparticles in rabbit eyes, Translational Vision Science & Technology, 9(6):20 (2020)

[Paper]  Exosome-based delievery of super-repressor IkBa relieves sepsis-associated
               organ damage and mortality, Science Advances, 6(15):eaaz6980 (2020)

[Paper]  Dll4 suppresses transcytosis for arterial blood-retinal barrier homeostasis
               Circulation Research, 126(6):767-783 (2020)

[Paper]  A novel pancreatic imaging window for stabilized longitudinal in vivo observation
               of pancreatic islets in murine model, Diabetes & Metabolism J., 44(1):193-198 (2019)

[Paper]  PM2.5 exposure in the respiratory system induces distinct inflammatory signaling
               in the lung and the liver of mice, J. of Immunological Research, 3486841 (2019)

[Paper]  3D cellular visualization of intact mouse tooth using optical clearing without
               decalcificationnovel, International Journal of Oral Science, 11:25 (2019)

[Paper]  In vivo longitudinal depth-wise visualization of tumorigenesis by needle-shaped
               side-view confocal endomicroscopy, Biomedical Optics Express, 10(6):2719 (2019)

[Paper]  Lissajous scanning two-photon endomicroscope for in vivo tissue imaging,
               Scientific Reports, 9:3560 (2019)
Welcome to In Vivo Micro-Visualization Lab.
What's New
Custom-built Intravital
Confocal Microscopy

In Vivo Micro-Visualization Laboratory

Graduate School of Medical Science and Engineering (GSMSE)
Graduate School of Nanoscience and Technology (GSNT)
Korea Advanced Institute of Science and Technology (KAIST)
HOME
PROFESSOR
RESEARCH
MEMBERS
PUBLICATION
GALLERY
LINK
CLASS
In Vivo Micro-Visualization Laboratory,  Graduate School of Nanoscience and Technology
College of Natural Science,  Korea Advanced Institute of Science and Technology (KAIST)
Rm.219, Basic Research Building (E6-6), 291 Daehak-ro, Yuseong, Daejeon, Republic of Korea, 34141
Tel. +82-42-350-1155,  Fax. +82-42-350-1110,  soyahn007@kaist.ac.kr,  Copyright (C) 2015
Last update. 2020. 09. 13.