In vivo visualization of lymph node showing HEV and T cell homing
T cells (red), blood vessel (green)
Ear skin of LysM-GFP mouse. Blood vessel was labeled by intravenous injection of anti-CD31 antibody cojugated Alexa647
Operation of custom-design, video-rate, intravital confocal microscopy system; starred by K. Choe
We are focusing on the development of the novelin vivo visualization techniques for the live animal in a single cell to single molecule resolution. In a recent decade, rapid advances of in vivo micro-visualization technologies have allowed us to catch a glimpse of numerous exciting processes such as gene expression, regulation, protein activity, drug delivery, systemic cell trafficking, cell-cell interaction, physiological response to external stimuli in the natural microenvironment in vivo. We're now on the verge of a new era of micro-nano-scale in vivo visualization technologies those can be utilized as a novel tool for basic and translational biomedical research as well as a valuable clinical tool for cellular-level diagnosis and monitoring.
Our ultimate goal is to open up a new avenue to answer questions in biomedical science those are important but difficult to investigate by pioneering innovative visualization technology. We are looking for a talented student and researcher in multiple disciplines including engineering, physics, chemistry, biology and medicine as an active interdisciplinary team-work is the cornerstone to accomplish our goal.
[Notice] Positions open for graduate student (MS/PhD), Post-doctoral researcher [email]
[Award] Kibaek Choe awarded Presentation Award at International Conference of
Korean Society for Molecular and Cellular Biology (KSMCB), Sep. 2017
[Award] Soyeon Ahn awarded Excellence Poster Awardat Korea Vascular Science and Medicine Organization Meeting (VSMO), Aug. 2017
[Award] Eunjoo Song awarded Best Paper Awardat Optics and Photonics Congress (OPC), Jul. 2017