Image Gallery
Recent Video
Lipid Droplet / Microvasculature visualized in vivo in 3D in the liver of Non-Alcoholic Fatty Liver Disease (NAFLD) mouse model
Liver Fibrosis visualzied in vivo by Second Harmonic Generation (SHG) Imaging in live nonalcholic fatty liver mouse model
Operation of custom-design, video-rate, intravital confocal microscopy system; starred by K. Choe
We are focusing on the development of the novel in vivo visualization techniques for the live animal in a single cell to single molecule resolution. In a recent decade, rapid advances of in vivo micro-visualization technologies have allowed us to catch a glimpse of numerous exciting processes such as gene expression, regulation, protein activity, drug delivery, systemic cell trafficking, cell-cell interaction, physiological response to external stimuli in the natural microenvironment in vivo. We're now on the verge of a new era of micro-nano-scale in vivo visualization technologies those can be utilized as a novel tool for basic and translational biomedical research as well as  a valuable clinical tool for cellular-level diagnosis and monitoring.

Our ultimate goal is to open up a new avenue to answer questions in biomedical science those are important but difficult to investigate by pioneering innovative visualization technology. We are looking for a talented student and researcher in multiple disciplines including engineering, physics, chemistry, biology and medicine as an active interdisciplinary team-work is the cornerstone to accomplish our goal.
[Notice] Positions open for graduate student (MS/PhD), Post-doctoral researcher  [email]

[Paper]  In Intravital longitudinal imaging of hepatic lipid droplet accumulation in a murine
               model for nonalcoholic fatty liver disease
               Biomedical Optics Express, 11(9):5132-5146 (2020),  Editor's Pick

[Paper]  In vivo longitudinal visualization of the brain neuroinflammatory response at the
               cellular level in LysM-GFP mice induced by 3-nitropropionic acid
               Biomedical Optics Express, 11(8):4835-4847 (2020)
[Paper]  In vivo imaging of the hyaloid vascular regression and retinal and choroidal vascular
               development in rat eyes using optical coherence tomography angiography
               Scientific Reports, 11:12901 (2020)

[Paper]  Micromirror-embedded coverslip assembly for bidirectional microscopic imaging
               Micromachines, 11(6):582 (2020)
[Paper]  Intraocular distribution and kinetics of intravitreally injected antibodies and
               nanoparticles in rabbit eyes, Translational Vision Science & Technology, 9(6):20 (2020)

[Paper]  Exosome-based delievery of super-repressor IkBa relieves sepsis-associated
               organ damage and mortality, Science Advances, 6(15):eaaz6980 (2020)

[Paper]  Dll4 suppresses transcytosis for arterial blood-retinal barrier homeostasis
               Circulation Research, 126(6):767-783 (2020)

[Paper]  A novel pancreatic imaging window for stabilized longitudinal in vivo observation
               of pancreatic islets in murine model, Diabetes & Metabolism J., 44(1):193-198 (2019)

[Paper]  PM2.5 exposure in the respiratory system induces distinct inflammatory signaling
               in the lung and the liver of mice, J. of Immunological Research, 3486841 (2019)

[Paper]  3D cellular visualization of intact mouse tooth using optical clearing without
               decalcificationnovel, International Journal of Oral Science, 11:25 (2019)

[Paper]  In vivo longitudinal depth-wise visualization of tumorigenesis by needle-shaped
               side-view confocal endomicroscopy, Biomedical Optics Express, 10(6):2719 (2019)

[Paper]  Lissajous scanning two-photon endomicroscope for in vivo tissue imaging,
               Scientific Reports, 9:3560 (2019)
Welcome to In Vivo Micro-Visualization Lab.
What's New
Custom-built Intravital
Confocal Microscopy

In Vivo Micro-Visualization Laboratory

Graduate School of Medical Science and Engineering (GSMSE)
Graduate School of Nanoscience and Technology (GSNT)
Korea Advanced Institute of Science and Technology (KAIST)
In Vivo Micro-Visualization Laboratory,  Graduate School of Nanoscience and Technology
College of Natural Science,  Korea Advanced Institute of Science and Technology (KAIST)
Rm.219, Basic Research Building (E6-6), 291 Daehak-ro, Yuseong, Daejeon, Republic of Korea, 34141
Tel. +82-42-350-1155,  Fax. +82-42-350-1110,,  Copyright (C) 2015
Last update. 2020. 09. 13.