Image Gallery
Recent Video
In vivo visualization of lymph node showing HEV and T cell homing
T cells (red), blood vessel (green)
Ear skin of LysM-GFP mouse. Blood vessel was labeled by intravenous injection of anti-CD31 antibody cojugated Alexa647
Operation of custom-design, video-rate, intravital confocal microscopy system; starred by K. Choe
We are focusing on the development of the novel in vivo visualization techniques for the live animal in a single cell to single molecule resolution. In a recent decade, rapid advances of in vivo micro-visualization technologies have allowed us to catch a glimpse of numerous exciting processes such as gene expression, regulation, protein activity, drug delivery, systemic cell trafficking, cell-cell interaction, physiological response to external stimuli in the natural microenvironment in vivo. We're now on the verge of a new era of micro-nano-scale in vivo visualization technologies those can be utilized as a novel tool for basic and translational biomedical research as well as  a valuable clinical tool for cellular-level diagnosis and monitoring.

Our ultimate goal is to open up a new avenue to answer questions in biomedical science those are important but difficult to investigate by pioneering innovative visualization technology. We are looking for a talented student and researcher in multiple disciplines including engineering, physics, chemistry, biology and medicine as an active interdisciplinary team-work is the cornerstone to accomplish our goal.
[Notice] Positions open for graduate student (MS/PhD), Post-doctoral researcher  [email]

[Award] Kibaek Choe awarded Presentation Award at International Conference of
             Korean Society for Molecular and Cellular Biology (KSMCB), Sep. 2017
[Award] Soyeon Ahn awarded Excellence Poster Award at
              Korea Vascular Science and Medicine Organization Meeting (VSMO), Aug. 2017
[Award] Eunjoo Song awarded Best Paper Award at Optics and Photonics Congress (OPC), Jul. 2017
[Award] Inwon Park awarded Reserach Fellowship Award from Yuhan Foundation, Jun. 2017

[Member] Sujung Hong newly joined IVMVL, May. 2017
[Member] Ryul Kim newly joined IVMVL, Mar. 2017

[Paper]  In Vivo Cellular-level Real-time Pharmacokinetic Imaging of Free-form and Liposomal
               Indocyanine Green in Liver, Biomedical Optics Express, accepted (2017)

[Paper]  Caspase-8 controls the secretion of inflammatory lysyl-tRNA synthetase in exosomes
               from cancer cell, J. of Cell Biology, DOI: 10.1083/jcb.20160511848 (2017)

[Paper]  VEGFR2 but not VEGFR3 governs integrity and remodeling of thyroid angiofollicular unit
               in normal state and during goitrogenesis, EMBO Molecular Medicine, 9:750-769 (2017)

[Paper]  Polypeptide-based polyelectrolyte complexes overcoming the biological barriers of
               oral insulin delivery, J. of Industrial and Engineering Chemistry, 48:79-87 (2017)

[Paper]  Sustained inflammation after pericyte depletion induces irreversible blood-retina
               barrier breakdown, JCI Insight, 2(3):e90905 (2017)

[Paper]  Secreted Tryptophanyl-tRNA Synthetase as a Primary Defense System against Infection,
               Nature Microbiology, 2:16191 (2016)

[Paper] Holographic intravital microscopy for 2-D and 3-D imaging intact circulating blood cells
               in microcapillaries of live mice, Scientific Reports, 6:33084 (2016)

[Paper]  Imaging laser-induced choroidal neovascularization in the rodent retina using optical
               coherence tomography, Investigative Ophthalmology & Visual Sci., 57:OCT331-OCT340 (2016)

[Paper] In vivo fluorescence retinal imaging following AAV2-mediated gene delivery in the rat retina
               Investigative Ophthalmology & Visual Science, 57(7):3390-3396 (2016)
Welcome to In Vivo Micro-Visualization Lab.
What's New
Custom-built Intravital
Confocal Microscopy

In Vivo Micro-Visualization Laboratory

Graduate School of Nanoscience and Technology (GSNT)
Korea Advanced Institute of Science and Technology (KAIST)
In Vivo Micro-Visualization Laboratory,  Graduate School of Nanoscience and Technology
College of Natural Science,  Korea Advanced Institute of Science and Technology (KAIST)
Rm.219, Basic Research Building (E6-6), 291 Daehak-ro, Yuseong, Daejeon, Republic of Korea, 34141
Tel. +82-42-350-1155,  Fax. +82-42-350-1110,,  Copyright (C) 2015
Spring Picnic, Jeonju, Korea  - May, 2017

Last update. 2017. 09. 18.