Image Gallery
Recent Video
In vivo visualization of lymph node showing HEV and T cell homing
T cells (red), blood vessel (green)
Ear skin of LysM-GFP mouse. Blood vessel was labeled by intravenous injection of anti-CD31 antibody cojugated Alexa647
Operation of custom-design, video-rate, intravital confocal microscopy system; starred by K. Choe
We are focusing on the development of the novel in vivo visualization techniques for the live animal in a single cell to single molecule resolution. In a recent decade, rapid advances of in vivo micro-visualization technologies have allowed us to catch a glimpse of numerous exciting processes such as gene expression, regulation, protein activity, drug delivery, systemic cell trafficking, cell-cell interaction, physiological response to external stimuli in the natural microenvironment in vivo. We're now on the verge of a new era of micro-nano-scale in vivo visualization technologies those can be utilized as a novel tool for basic and translational biomedical research as well as  a valuable clinical tool for cellular-level diagnosis and monitoring.

Our ultimate goal is to open up a new avenue to answer questions in biomedical science those are important but difficult to investigate by pioneering innovative visualization technology. We are looking for a talented student and researcher in multiple disciplines including engineering, physics, chemistry, biology and medicine as an active interdisciplinary team-work is the cornerstone to accomplish our goal.
[Notice] Positions open for graduate student (MS/PhD), Post-doctoral researcher  [email]
   
[Award] Eunji Kong, awarded Travel Grant Award, Max Planck Florida, Insititute for Neuoscience
               Neuroimaging Techniques Workshop, Jupiter, Florida, USA, Feb. 2019
[Award] Jingu Lee, awarded Best Poster Award, Korean Organoid Society Annual Meeting
               Seoul, Korea, Nov. 2018
[Award] Jieun Moon, awarded Best Poster Award, Korean Society of Vascular Biology and
               Medicine Annual Meeting, Daejeon, Korea, Oct. 2018
[Award] Soyeon Ahn, awarded Best Poster Award, 16th Korea-Japan Joint Symposium on
               Vascular Biology, Osaka, Japan, Sep. 2018
   
[Paper]  3D cellular visualization of intact mouse tooth using optical clearing without
               decalcificationnovel, International Journal of Oral Science, accepted

[Paper]  A novel pancreatic imaging window for stabilized longitudinal in vivo observation
               of pancreatic islets in murine model, Diabetes & Metabolism J., accepted

[Paper]  In vivo longitudinal depth-wise visualization of tumorigenesis by needle-shaped
               side-view confocal endomicroscopy,Biomedical Optics Express, 10(6):2719 (2019)

[Paper]  Lissajous scanning two-photon endomicroscope for in vivo tissue imaging,
               Scientific Reports, 9:3560 (2019)

[Paper]  Neutrophils disturb pulmonary microcirculation in sepsis-induced acute lung injury,
               European Respiratory Journal, 53:1800736 (2019)

[Paper]  Tie2 activation promotes choriocapillary regeneration for alleviating neovascular
               age-related macular degeneration, Science Advances, 5(2):eaau6732 (2019)

[Paper]  Quantitative Quinic acid-conjugated nanoparticles enhance drug delivery to solid tumors
               via interactions with endothelial selectins, Small, 14(50):1803601 (2018)

[Paper]  Quantitative two-photon microscopy imaging analysis of human skin to evaluate
               enhanced transdermal delivery by hybrid-type multi-lamellar nanostructure, 
               Biomedical Optics Express, 9(8):3974 (2018)
 
[Paper]  Nanoparticle-assisted transcutaneous delivery of a signal transducer and activator of
               transcription 3-inhibiting peptide ameliorates psoriasis-like skin inflammation
               ACS Nano, 12(7):6904-6916 (2018)
Welcome to In Vivo Micro-Visualization Lab.
What's New
Custom-built Intravital
Confocal Microscopy

In Vivo Micro-Visualization Laboratory

Graduate School of Nanoscience and Technology (GSNT)
Graduate School of Medical Science and Engineering (GSMSE)
Korea Advanced Institute of Science and Technology (KAIST)
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In Vivo Micro-Visualization Laboratory,  Graduate School of Nanoscience and Technology
College of Natural Science,  Korea Advanced Institute of Science and Technology (KAIST)
Rm.219, Basic Research Building (E6-6), 291 Daehak-ro, Yuseong, Daejeon, Republic of Korea, 34141
Tel. +82-42-350-1155,  Fax. +82-42-350-1110,  soyahn007@kaist.ac.kr,  Copyright (C) 2015
Last update. 2019. 05. 21.