Image Gallery
Recent Video
In vivo visualization of lymph node showing HEV and T cell homing
T cells (red), blood vessel (green)
Ear skin of LysM-GFP mouse. Blood vessel was labeled by intravenous injection of anti-CD31 antibody cojugated Alexa647
Operation of custom-design, video-rate, intravital confocal microscopy system; starred by K. Choe
We are focusing on the development of the novel in vivo visualization techniques for the live animal in a single cell to single molecule resolution. In a recent decade, rapid advances of in vivo micro-visualization technologies have allowed us to catch a glimpse of numerous exciting processes such as gene expression, regulation, protein activity, drug delivery, systemic cell trafficking, cell-cell interaction, physiological response to external stimuli in the natural microenvironment in vivo. We're now on the verge of a new era of micro-nano-scale in vivo visualization technologies those can be utilized as a novel tool for basic and translational biomedical research as well as  a valuable clinical tool for cellular-level diagnosis and monitoring.

Our ultimate goal is to open up a new avenue to answer questions in biomedical science those are important but difficult to investigate by pioneering innovative visualization technology. We are looking for a talented student and researcher in multiple disciplines including engineering, physics, chemistry, biology and medicine as an active interdisciplinary team-work is the cornerstone to accomplish our goal.
[Notice] Positions open for graduate student (MS/PhD), Post-doctoral researcher  [email]
   
[Award] Soyeon Ahn, awarded Young Scientist Program Fellowship, IUBMB SEOUL 2018,
               Jun. 2018
[Award] Inwon Park, awarded Samsung HumanTech Paper Award, Samsung Electronics,
               Feb. 2018
[Award] Hown Seo, awarded Young Investigator Best Research Award, Annual Biophotonics
              Conference (ABC), Oct. 2017
[Award] Kibaek Choe, awarded Presentation Award at International Conference of
              Korean Society for Molecular and Cellular Biology (KSMCB), Sep. 2017
[Award] Soyeon Ahn, awarded Excellence Poster Award, Korea Vascular Science and
              Medicine Organization Meeting (VSMO), Aug. 2017
   
[Paper]  Quantitative two-photon microscopy imaging analysis of human skin to evaluate
               enhanced transdermal delivery by hybrid-type multi-lamellar nanostructure, 
               Biomedical Optics Express, 9(8):397403982 (2018)
 
[Paper]  Nanoparticle-Assisted Transcutaneous Delivery of a Signal Transducer and Activator of
               Transcription 3-Inhibiting Peptide Ameliorates Psoriasis-like Skin Inflammation
               ACS Nano, 12(7):6904-6916 (2018)

[Paper]  Intravital Imaging of Pulmonary Endothelial Surface Layer in Murine Sepsis Model,
               Biomedical Optics Express, 9(5):2383-2393 (2018)

[Paper]  Highly angiogenic, nonthrombogenic bone marrow mononuclear cell-derived spheroids
               in intraportal islet transplantation, Diabetes, 67(3):473-485 (2018)
   
[Paper]  Effect of resveratrol treatment on graft revascularization after islet transplantation
               in streptozotocin-induced diabetic mice, Islets, 10(1):25-39 (2018)
   
[Paper]  Intravital longitudinal wide-area imaging of dynamic bone marrow engraftment and
               multilineage differentiation through nuclearcytoplasmic labeling,
               PLoS ONE, 12(11):e0187660 (2017)
  
[Paper]  In vivo cellular-level real-time pharmacokinetic imaging of free-form and liposomal
               indocyanine green in liver, Biomedical Optics Express, 8(10):4706-4716 (2017)

[Paper]  VEGFR2 but not VEGFR3 governs integrity and remodeling of thyroid angiofollicular unit
               in normal state and during goitrogenesis, EMBO Molecular Medicine, 9:750-769 (2017)
Welcome to In Vivo Micro-Visualization Lab.
What's New
Custom-built Intravital
Confocal Microscopy

In Vivo Micro-Visualization Laboratory

Graduate School of Nanoscience and Technology (GSNT)
Graduate School of Medical Science and Engineering (GSMSE)
Korea Advanced Institute of Science and Technology (KAIST)
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In Vivo Micro-Visualization Laboratory,  Graduate School of Nanoscience and Technology
College of Natural Science,  Korea Advanced Institute of Science and Technology (KAIST)
Rm.219, Basic Research Building (E6-6), 291 Daehak-ro, Yuseong, Daejeon, Republic of Korea, 34141
Tel. +82-42-350-1155,  Fax. +82-42-350-1110,  soyahn007@kaist.ac.kr,  Copyright (C) 2015
Last update. 2018. 08. 01.